Office : School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology 111 University Ave, Muang District, Nakhon Ratchsima, 30000 Thailand

Phone : +66 (0)92-664-1118

E-mail : p.noisa@sut.ac.th

Education :

2014 Postdoctoral Researcher, University of Helsinki, Finland           
2010 Ph.D. in Stem Cell Technology, Imperial College London, UK
2003 B.Sc. in Biology, Mahidol University, Thailand

Work experience :

2010 – Present Lecturer, Suranaree University of Technology, Thailand

Research Expertise & Interest :

Cell Biology : Generation of induced pluripotent stem cells Maintenance & characterization of human stem cells Differentiation of human stem cells Immunofluorescence and confocal microscopy Cell cycle, proliferation and apoptosis assays Fluorescence- and magnetic-activated cell sortings Flow cytometry analysis
Molecular Biology :Real time and semi-quantative PCR Recombinant DNA technique, plasmid cloning and expression RNA interference technology Transgenic mammalian cell line productions Western, Northern and Southern blottings Quantitative colourimetric enzyme and luciferase assays

Research experiences :

Postdoctoral Project : Modeling normal and aberrant neural crest development in humans by using human pluripotent stem cells Supervisors: Prof. Taneli Raivio
Ph.D. thesis : Characterization of neural progenitor/stem cells derived from human embryonic stem cells Supervisor: Dr. Wei Cui
Project in Biochemistry : Development of cytokine-induced killer cells against cholangiocarcinomas Supervisors: Assoc. Prof. Dr. Rutaiwan Tohtong
Final year B.Sc. Project : Expression of a calcium-binding protein gene from Fasciola gigantica in yeast system Supervisor: Assoc. Prof. Dr. Suksiri Vichasri-Grams
Summer B.Sc. Project : Characterization of chromosomal polymorphism of brain tumors by PCR-SSCP Supervisor: Assoc. Prof. Dr. Wipawan Tungnipon

Awards, Funding & Memberships :

Academy of Finland Research Fellowship 2012
The Sigrid Juselius Foundation Awardee 2012
Awardee of the British Society of Cell Biology Travel award 2009
Awardee of the International Consortium Stem Cell Network 2008
Recipient of the Royal Thai Government Scholarship 2006 – 2010
Recipient of the Ministry of Science and Technology Scholarship 1996 – 2005  
Member of the International Society for Stem Cell Research 2009 – Present
Member of the British Society of Cell Biology 2007 – Present
Member of European EStools consortium: 2006 – 2009  

Professional Development and Meetings :

– The International Society for Stem Cell Research Annual Meeting 2013 Boston, USA 
EMBL Conference: Stem Cells in Cancer and Regenerative Medicine 2012 Heidelberg, Germany
– The UK Stem Cell Network Meeting  2011 York, the UK
– The international Stem Cell Initiatives Annual Meeting 2010 Manchester, the UK
– The International Society for Stem Cell Research Annual Meeting 2009 Barcelona, Spain
– The International Consortium Stem Sell Network Annual Meeting 2008 Vancouver, Canada
– European Stem Cell Consortium 2008 Budapest, Hungary
– Joint meeting: Imperial College and Genome Institute of Singapore 2007 London, the UK
– FACS Workshop on Human Embryonic Stem Cells 2007 Sheffield, the UK
– Symposium in Stem cell Repair and Regeneration 2007 London, the UK
– 25 Years of Embryonic Stem Cells 2006 Cambridge, the UK            

Research publications :

Total number of publication: 14 (International journals)
h-index: 5
Total citation: 151

• Wu, J., Habegger, L., Noisa, P., Szekely, A., Qiu, C., Hutchison, S., Raha, D., Egholm, M., Lin, H., Weissman, S., Cui, W., Gerstein, M, Snyder, M., Dynamic Transcriptomes during Neural Differentiation of Human Embryonic Stem Cells Revealed by Short, Long, and Paired-end Sequencing, Proc Natl Acad Sci USA, 2010; 16;107(11):5254-9.
• Noisa, P., Urrutikoetxea-Uriguen, A., Li, M., Cui, W., Generation of Human Embryonic Stem Cell Reporter Lines Expressing GFP Specifically in Neural Progenitors, Stem Cell Rev, 2010 Sep;6(3):438-49
• Noisa, P., Urrutikoetxea-Uriguen, A., Cui, W., Generation of Human Embryonic Stem Cells Carrying Lineage Specific Reporters, Methods Mol Biol, 2011;690:95-106
• Imsoonthornruksa, S., Noisa, P., Parnpai, R., Ketudat-Cairns, M., A Simple Method for Production and Purification of Soluble and Biologically Active Recombinant Human Leukemia Inhibitory Factor (hLIF) Fusion Protein in Escherichia coli,
• J Biotechno, 2011; 20; 151(4):295-302
• Surmacz, B., Noisa, P., Risner-Janiczek, JR., Hui, K., Ungless, M., Cui, W., Li, M., DLK1 Promotes Neurogenesis of Human and Mouse Pluripotent Stem Cell-Derived Neural Progenitors Via Modulating Notch and BMP Signalling. Stem Cell Rev, 2011;doi: 10.1007/s12015-011-9298-7
• Noisa, P., Parnpai, R., Technical Challenges in the Derivation of Human Pluripotent Cells. Stem Cells Int. 2011;2011:907961 (Review)
• Kunkanjanawan, T., Noisa, P., Parnpai, R., Modeling Neurological Disorders by Human Induced Pluripotent Stem Cells. J Biomed Biotechnol, 2011:350131 (Review)
• Noisa, P., Ramasamy, S. T., Lamont, R.F., Yu, L. S. J., Sheldon, M., Russell, A., Jin, X., Cui, W., Identification and Characterisation of the Early Differentiating Cells in Neural Differentiation of Human Embryonic Stem Cells. PLOS One, 2012; doi:10.1371/journal.pone.0037129
• Tommiska, J., Toppari, J., Vaaralahti, K., Känsäkoski, J., Laitinen, E.M., Noisa, P., Kinnala, A., Niinikoski, H., Raivio, T., PROKR2 mutations in autosomal recessive Kallmann syndrome. Fertil Steril, 2012; doi:1016/j.fertnstert.2012.11.003
• Jongkamonwiwat, N., Noisa, P., Biomedical and clinical promises of human pluripotent stem cells for neurological disorders. Biomed Res Int, 2013; doi: 10.1155/2013/656531 (Review)
• Noisa, P., Lund, C., Kanduri, K., Lund, R., Lähdesmäki, H., Lahesmaa, R., Lundin, K., Chokechuwattanalert, H., Otonkoski, T., Tuuri, T., Raivio, T., Notch signaling regulates the differentiation of neural crest from human pluripotent stem cells. J Cell Sci. 2014;doi: 10.1242/jcs.145755
• Noisa, P., Raivio, T., Neural crest cells: From developmental biology to clinical interventions. Birth Defects Res C Embryo Today. 2014 Sep 16. doi: 10.1002/bdrc.21074. (Review)
• Suksuphew, S., Noisa, P., Neural stem cells could serve as a therapeutic material for age-related neurodegenerative diseases. W J of Stem Cells. 2014, in press (review)
• Noisa P., Raivio T., Cui W., Neural Progenitor Cells Derived from Human Embryonic Stem Cells as an Origin of Dopaminergic Neurons. Stem Cells Int. 2015;2015:647437. doi: 10.1155/2015/647437. Epub 2015 Apr 30.
• Trokovic R., Weltner J., Noisa P., Raivio T., Otonkoski T., Combined negative effect of donor age and time in culture on the reprogramming efficiency into induced pluripotent stem cells. Stem Cell Res. 2015 Jun 11. pii: S1873-5061(15)00074-4. doi: 10.1016/j.scr.2015.06.001.