Education :

2016 Ph.D. (Microbiology), University of California, Davis, USA
2004 M.Sc. (Clinical Pathology), Mahidol University, Thailand
1997 B.Sc. (Medical Technology), Khon Kaen University, Thailand              

Work experience :

2011-present A graduate student in Gelli Lab, Microbiology Graduate Group, UC Davis Research focuses on mechanisms of Cryptococcus neoformans in invading the central nervous system (CNS). My research project is “The Ephrin receptor tyrosine kinase, EphA2, promotes the migration of Cryptococcus neoformans across the blood-brain barrier”. I have been using several molecular techniques such as RT-PCR, qPCR, cloning, biolistics transformation, cell cultures, transcytosis assay, adhesion assay, siRNA gene knockdown, Western Blot assay, etc.

• A teaching assistant in Genetics and Biotech Lab (BIT161A) in Winter quarter 2014 at UC Davis.
• A teaching assistant in Microbiology Laboratory (MIC101L) in Spring quarter 2015 at UC Davis.
• A teaching assistant in Genetics and Biotech Lab (BIT161A) in Summer session I 2015 at UC Davis.
• A teaching assistant in Microbiology Laboratory (MIC103L) in Fall and Winter quarter 2015 at UC Davis.

1997-2010 A medical technologist in Microbiology Laboratory, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

• Identify pathogenic microorganisms such as bacteria, fungus, yeast, and mycobacterium isolated from patients
• Utilize techniques such as direct examination and conventional cultural methods followed by biochemical tests
• Perform susceptibility tests of pathogenic organisms by disk diffusion methods and MIC method A teaching assistant in Microbiology Laboratory class
• Teach medical students at Mahidol University, Thailand

Training :

Sep 9-11, 2013 RNA seq workshop, Bioinformatics core, University of California, Davis.
Jul – Sep 2002 Trained as a research fellow studying “ Nosocomial Infections and Drug-resistant Microorganisms” at the Division of Microbiology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Jul – Sep 2000 Trained as a research fellow studying “ Nosocomial Infections and Drug-resistant Microorganisms” at the Division of Microbiology, Faculty of Medicine, Juntendo University, Tokyo, Japan.

Research Expertise & Interest :

Expertise in identification of pathogenic microorganisms such as bacteria, fungus, yeast, and mycobacterium isolated from patients. Examine of drug susceptibility in the pathogens isolated from the patients. Study of host and microbe interactions to understand microbial pathogenesis, especially in Cryptococcus neoformans that can cross Blood Brain Barrier (BBB) by using ligands and receptors for the interactions, leads to finding the ways to prevent the infections.

Research publications :

Total number of publication: (International journals)

Total citation:

• Kiem Vu, Rick Tham, John P. Uhrig, George R. Thompson III, Sarisa Na Pombejra, Mantana Jamklang, Jenifer M. Bautos, Angie Gelli. Invasion of the Central Nervous System by Cryptococcus neoformans requires a Secreted Fungal mBio. 3 June 2014, Volume 5 issue 3 e01101-14.
• Hong MP, Vu K, Bautos JM, Tham R, Jamklang M, Uhrig JP, Gelli A. Activity of calcium channel pore Cch1 is dependent on a modulatory region of the subunit Mid1 in Cryptococcus neoformans. Eukaryot Cell. 2013 Jan; 12(1):142-50.
• Chongtrakool P, Ito T, Ma XX, Kondo Y, Trakulsomboon S, Tiensasitorn C, Jamklang M, Chavalit T, Song JH, Hiramatsu K. Staphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries: a proposal for a new nomenclature for SCCmec elements. Antimicrob Agents Chemother. 2006 Mar;50(3):1001-12.
• Jamklang M, Santanirand P. Beta-lactamase enzymes in Gram-negative bacteria. Journal of Medical Technology. 2005, Year 33, Vol 3, page 1187-1197.
• Daum RS, Ito T, Hiramatsu K, Hussain F, Mongkolrattanothai K, Jamklang M, Boyle-Vavra S. A novel methicillin-resistance cassette in community-acquired methicillin-resistant Staphylococcus aureus isolates of diverse genetic J Infect Dis. 2002 Nov 1;186(9):1344-7. Epub 2002 Oct 3.
• Ma XX, Ito T, Tiensasitorn C, Jamklang M, Chongtrakool P, Boyle-Vavra S, Daum RS, Hiramatsu K. Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus Antimicrob Agents Chemother. 2002 Apr; 46(4):1147-52.

Presentations

• Poster presentation at 6th International Symposium on Antimicrobial Agents and Resistance, March 7-9, 2007, Singapore. Jamklang M, Santarasamit P, Nathisuwan, Chongtrakool P, and Santanirand P. ESBL-producing Providencia stuartii in a university hospital, Bangkok, Thailand.
• Oral Presentation at 114th General Meeting American Society for Microbiology, May 17-20, 2014, Boston, Massachusetts. Cryptococcus neoformans Invades the Central Nervous System by Secreting a Newly Identified Metalloprotease. Mantana Jamklang, John P. Uhrig, Sarisa Na Pombjera, Angie Gelli.

• Poster presentation at Microbial Pathogenesis and Host Response, September 8-12, 2015, Cold Spring Laboratory. Transcriptome of Human Brain Endothelial cells challenged with Cryptococcus neoformans reveals a central role for a tyrosine kinase receptor-mediated pathway. Mantana Jamklang, John Uhrig, Angie Gelli.